A long lost key opens an ancient lock: Drosophila Myb causes a synthetic multivulval phenotype in nematodes
The five-protein MuvB core complex is highly conserved in Spoons animals.This nuclear complex interacts with RB-family tumor suppressor proteins and E2F-DP transcription factors to form DREAM complexes that repress genes that regulate cell cycle progression and cell fate.The MuvB core complex also interacts with Myb family oncoproteins to form the